Iron based anemia

PaintNLady

I would like to know how much being very anemic has on lactic acid production.
I am having lots of problems with fatigue and leg burning while biking. So, I wonder if it is because I am out of shape or because of my iron deficency.

I realized one week ago that I had dipped into my low iron stage and have begun taking iron and vitamin E. This time I will continue taking the iron until I have a blood test that is in the normal range, even if that is just barely "normal".

And yes I am working with a Dr.

2LAP

Both systems are seperate, so there shouldn't be a direct effect of one on the other.

If you are aneamic you wouldn't be able to work as hard as normal because your blood doesn't carry as much oxygen as normal. If you train the the same way (i.e. same speed over the same terrain) you may find that you are working reletivly harder, resulting in lactate accumulation.

Red blood cells also buffer lactate, so if your heamatocrit is low you might find that increases in lactate are more damaging to your performance.

All in all, get your iorn back up (and find out why you are aneamic) while taking it easier on the bike when you feel you need to. When you are recovered training at lactate threshold and anaerobic training (e.g. maximal sprints of 45 seconds) will help you cope better with lactate.

Insight Driver

All in all, get your iorn back up (and find out why you are aneamic) while taking it easier on the bike when you feel you need to. When you are recovered training at lactate threshold and anaerobic training (e.g. maximal sprints of 45 seconds) will help you cope better with lactate. [/QUOTE]

Ok....thanks. One more question comes to mind now.....Once I am in that lactate burn, if I can force myself to continue with more intensity, will the burn stop or is it I who has to slow down and let the body clear out the lactic acid???? In other words can you "work" thro a burn?

PaintNLady

OOOPS.....I was not logged in under my username.....Insight Driver is my husband

2LAP

When your legs are burning, the only way you can stop them burning is to slow down a little. Maintaining or increasing the pace will only increase the lactate more resulting in more burn or your legs slowing down/weakening until you recover.

The lactate burn shouldn't always be seen as a bad thing and is a sign that some training sessions (ananerobic) are going well.

Seecyd

It seems a lot of people complain about the symptoms of anemia. I have heard that V B12 helps the body to absorb iron [injested through foods]. You have to be careful of iron overloading your system. I have read a bit about the imbalance of Iron --as in too much-- and heart problems, especially in the genes of many coming from the british isles. I'm not an expert, but I'd be careful.

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kokopuffs

A few facts about B12:

1. it's an animal product though furnished by soy in small amounts. So vegetarians may need a B12 supplement to avoid Pernicious Anemia;

2. alcoholics may require B12 injections since alcoholism impares the body's ability to absorb it.

Pacesetter

when you feel the 'burn' this is when lactate production is greater than the body's ability to get rid of it. If you can you should try to cycle alittle longer with the burn, this will, after time help your body become more efficient. Another term for this is Anaerobic Threshold training, by pushing up your AT, you will eventually be able to ride at a higher intensity for longer.

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patch70

Strictly speaking, pernicious anaemia is due to a lack of 'intrinsic factor' which is produced by the stomach to allow Vit B12 to get absorbed in the last part of the small intestine. Hence, vegetarians can get B12 deficient leading to 'megaloblastic anaemia' but it is not called 'pernicious anaemia'.

Also, PaintNLady, Vitamin C will help you absorb Iron by encouraging the iron to go from Ferric (Fe3+) to Ferrous (Fe2+). The latter is absorbable, the former is not. I presume you meant to say Vit C rather than Vit E???

To Seecyd, apart from people with inheritable iron overload conditions (eg haemochromatosis which occurs in 5 out of every 1000 white people, less in other races), it is very hard to overdose on iron. You only absorb a very small proportion of that which you eat.

kokopuffs

Pernicious anemia is due either to a lack of B12 ingestion or intrinsic factor, one or the other.

patch70

Sorry, but what I wrote was correct. Check any medical textbook if you like.
There are many causes of B12 deficiency and 'pernicious anaemia' is only one of them - and it is due to a lack of intrinsic factor.

kokopuffs

Sorry, but review what you wrote.

Pernicious anemia is the RESULT AND NOT THE CAUSE of B12 deficiency. Anemia does not cause a B12 deficiency. It's the end result.

I'm a chiropractor and I've taught Health Science including anemias for several years.

Go read the MERCK MANUAL.

patch70

You are probably not teaching it very well then but hopefully your students read textbooks. You could try Harrisons or UpToDate.
Here is a list of causes of B12 deficiency:
Gastric causes:
-Pernicious anaemia
-gastrectomy
Small intestinal causes:
-Malabsorption
-Ileal resection or bypass
-Crohn's disease
-Blind loop syndrome
Pancreatic cause:
-Pancreatic insufficiency
Diet:
-Strict vegans, especially during pregnancy
Agents that block absorption (rare):
-Neomycin
-Biguanides (eg metformin)
-Proton pump imhibitors (eg omeprazole)
Inherited transcobalamin II deficiency

As I said before and as this list demonstrates, there are many causes of B12 deficiency. Any of these can lead to megaloblastic anaemia or other manifestations such as subacute combined degeneration of the cord, axonal degeneration or dementia.

Pernicious anaemia is the major cause of B12 deficiency, accounting for over 75 percent of cases.
Pernicious anaemia is thought to result from an autoimmune attack on gastric intrinsic factor. Anti-intrinsic factor antibodies are detectable in the serum in up to 70 percent of patients with PA.

I trust you will understand this time but let me know if you want it simpler.

kokopuffs

Since you want to engage in ad hominem attacks, please get your head out of your ass, idiot.